This paper presents the design of mango distribution center and logistic in Chachoengsao province, using Richard Muther’s method. The research involved identification of characteristic and quantitative data, activity determination, activity flow analysis, relationship diagram, space requirement, and plant facility. The result showed that the mango distribution center and logistic should be consisted of the followings; receiving mangoes from farmers, classifying size and inspecting quality, weighing, packaging, storing, preparing for delivery, and processing documents. The total area was 4800 m2, including areas for loading, receiving, selecting and checking, weighing, storing, preparing for delivery, equipment room, and office, all in the same building.